A Randomized Phase 2 Trial of Axitinib/Nivolumab Combination Therapy vs. Single Agent Axitinib or Nivolumab for the Treatment of TFE/Translocation Renal Cell Carcinoma (tRCC) Across All Age Groups

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Updated on 19 February 2024

Summary

This phase II trial studies how well axitinib and nivolumab works in treating patients with TFE/translocation renal cell carcinoma that cannot be removed by surgery or has spread to other places in the body.

Description

Axitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving axitinib and nivolumab may work better in treating patients with TFE/translocation renal cell carcinoma compared to standard treatment, including surgery, chemotherapy, or immunotherapy.

Details
Condition Translocation Renal Cell Carcinoma (tRCC),Translocation Renal Cell Carcinoma,Renal Cell Carcinoma,tRCC,renal,kidney,renal cancer,kidney cancer,cancer,oncology
Age 1years - 100years
Clinical Study IdentifierTX10159
Last Modified on19 February 2024

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