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Phase 3 Accelerated BEP Trial: A randomised phase 3 trial of accelerated versus standard BEP chemotherapy for patients with intermediate and poor-risk metastatic germ cell tumours

Study of Accelerated vs. Standard Chemotherapy for Metastatic Germ Cell Tumors

Recruiting
11-45 years
All

This study investigates the effectiveness of an accelerated chemotherapy regimen compared to the standard regimen for treating metastatic germ cell tumors (GCTs). Germ cell tumors are a type of cancer that begins in the cells that form sperm or eggs. The study aims to see if the accelerated treatment is more effective without being more toxic than the standard treatment.

Participants will be randomly assigned to one of two study arms. One arm will receive the accelerated chemotherapy regimen, while the other will receive the standard regimen. Chemotherapy involves using drugs to kill cancer cells, and the study will monitor the effectiveness and side effects of each treatment.

  • Who can participate: Participants must be between 11 and 45 years old. They must have a confirmed diagnosis of germ cell tumor or certain high tumor marker levels indicating GCT.
  • Study details: Participants will be assigned to either an accelerated or standard chemotherapy regimen. The study will compare the effectiveness and side effects of the two regimens.
Study details
    Germ Cell Tumor

TX10204

19 February 2024

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