This study investigates the relationship between rosacea, a skin condition causing redness and visible blood vessels, and the sympathetic nervous system, which is part of the nervous system that controls the body's 'fight or flight' response. Researchers at Indiana University are looking at how rosacea might be linked to this part of the nervous system.

Participants will have pharmaceutical agents applied to their skin. The study includes two screening visits, each lasting about 30 minutes, followed by two sessions that each last between 3 to 4.5 hours. Minor financial compensation is provided for participation.

• Who can participate: Healthy men and non-pregnant/non-lactating women aged 18 to 45 years with mild to moderate rosacea can participate. Healthy individuals without rosacea are also needed as control subjects.
• Study details: Participants will have investigational pharmaceutical agents applied to their skin. The study involves two screening visits and two main sessions.
• Study Visits: The study requires 4 visits.