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A Phase II Study Evaluating Efficacy and Safety of Hypomethylating Agent Guadecitabine in Combination with Carboplatin in Extensive Stage Small Cell Lung Cancer

Study on Investigational Medication Combination with Chemotherapy for Small Cell Lung Cancer

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18 years and older
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This study investigates the effectiveness of combining an investigational medication with carboplatin for treating small cell lung cancer. Small cell lung cancer is a type of cancer that usually starts in the breathing tubes and spreads quickly. The study aims to compare this combination to the usual treatment methods to see which is more effective.

Participants in the study will receive either the investigational medication with carboplatin or the standard treatment. The study will involve regular monitoring and assessments to understand the effects and safety of the treatments.

  • Who can participate: Participants must not have had more than one prior chemotherapy treatment; previous immunotherapy is allowed. Male and female participants capable of having children must use effective birth control during and after the study.
  • Study details: Participants will be divided into study arms to receive either the investigational medication with carboplatin or the standard treatment, with regular monitoring to assess effects and safety.
Study details
    Small Cell Lung Cancer

TX10264

19 February 2024

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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