This study investigates the safety and effectiveness of an investigational medication compared to a placebo in treating moderate to severe atopic dermatitis. Atopic dermatitis, also known as eczema, is a condition that makes the skin red and itchy. The study is for adolescents aged 12-17 and adults aged 18-75 who are candidates for systemic therapy, which means they need treatment that affects the entire body.
Participants will receive either the investigational medication or a placebo, both in combination with topical corticosteroids. A placebo is an inactive substance that looks like the investigational medicine but does not contain any medicine. The study will involve various procedures, including medical history reviews, laboratory tests, and physical exams.
- Who can participate: Participants must be in general good health apart from having chronic atopic dermatitis for at least 3 years. They should have used a moisturizer twice daily for at least 7 days before the Baseline Visit. Females must not be pregnant and must use effective birth control during the study.
- Study details: Participants will either receive the investigational medication or a placebo, which is a pill without any active substance, along with topical corticosteroids. They will undergo medical history reviews, laboratory tests, and physical exams to monitor their health.
