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SURG-DUKE-CEPPA-VAC; A Randomized Phase II Evaluation of Negative Pressure Wound Therapy for Reduction of Postoperative Surgical Site Infection in Patients Undergoing Colorectal and Hepatopancreatobiliary Surgery

Investigating Surgical Site Infection Rates with Different Wound Therapies

Recruiting
18 years and older
All
Phase N/A

The purpose of this study is to evaluate if using incisional negative pressure wound therapy (NPWT) can reduce the rate of infections at the site of surgery. This study focuses on patients who are undergoing colorectal or hepatopancreatobiliary surgeries. Surgical site infections are infections that occur after surgery in the part of the body where the surgery took place. Negative pressure wound therapy involves using a vacuum dressing to promote healing in acute or chronic wounds and enhance healing of second and third degree burns.

Participants in this study will be divided into two study arms. One arm will receive traditional wound care, while the other will receive negative pressure wound therapy after their surgeries. This study will help determine if negative pressure wound therapy is more effective at reducing surgical site infections compared to traditional methods.

  • Who can participate: Individuals scheduled for elective colorectal or hepatopancreatobiliary surgeries, such as hemicolectomy or pancreatectomy, may participate. Participants must not require emergency or laparoscopic surgery and should not have pre-existing infections or severe medical conditions.
  • Study details: Participants will be assigned to either traditional wound care or negative pressure wound therapy after surgery. Negative pressure wound therapy uses a vacuum dressing to help wounds heal. The study will compare the infection rates between these two methods.
Study details
    colorectal surgery

TX7027

19 February 2024

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