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Phase I Study of Lonsurf in Combination with Gemcitabine and Nab-Paclitaxel in Patients with Advanced Pancreatic Ductal Adenocarcinoma (PDAC)

Investigating the Safety and Effects of a Chemotherapy Combination for Pancreatic Cancer

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18 years and older
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This study investigates the safety and effects of combining an investigational medication with other chemotherapy agents for the treatment of pancreatic cancer. Pancreatic cancer is a disease where cells in the pancreas grow uncontrollably. The purpose of this study is to see how well this combination works and to identify any side effects.

Participants in the study will receive a combination of chemotherapy treatments. Chemotherapy is a type of cancer treatment that uses drugs to stop the growth of cancer cells. The study will involve regular monitoring and assessments to evaluate the treatment's impact on the participants.

  • Who can participate: Adults with untreated locally advanced pancreatic cancer, confirmed through tests, can participate. Participants must have adequate organ function and women of childbearing potential must test negative for pregnancy before starting the study.
  • Study details: Participants will receive a combination of chemotherapy drugs, including an investigational medication. The treatment will be administered under close supervision to monitor safety and effects.
Study details
    pancreatic cancer
    Pancreatic Ductal Adenocarcinoma

TX10501

19 February 2024

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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