Phase I trial of azacitidine plus nivolumab following reduced-intensity allogeneic PBSC transplantation for patients with AML and high-risk myelodysplasia

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Updated on 19 February 2024

Summary

The purpose of this study is to find the maximum safe dose of nivolumab alone, and of nivolumab combined with azacitidine after reduced-intensity allogeneic peripheral blood stem cell (PBSC) transplantation. Another purpose is to see how the study drugs affect different aspects of transplant such as infection and disease response.

Details
Condition Myelodysplasia,Chronic Myelomonocytic Leukemia,Acute Myeloid Leukemia,Myelodysplastic Syndrome
Age 18years - 100years
Clinical Study IdentifierTX10509
Last Modified on19 February 2024

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