This study investigates two different methods for preventing graft-versus-host disease (GVHD) in patients who have undergone a transplant. GVHD is a condition where the transplanted cells attack the recipient's body. The study aims to see which method better supports survival without GVHD or cancer relapse over one year.
Participants will undergo specific procedures to monitor their health and the effectiveness of the GVHD prevention methods. These procedures help ensure that the investigational approaches are safe and effective for patients.
- Who can participate: Adults with a left ventricular ejection fraction of at least 45% can participate. Women must use two effective birth control methods or abstain from heterosexual intercourse, while men must use barrier contraception or abstain.
- Study details: Participants will receive one of two GVHD prevention treatments. A placebo is not involved in this study.
- Study Timelines: The study will last 1 year.
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