An Open-Label Randomized Phase II Study of Combining Osimertinib with and without Ramucirumab in TKI-naïve EGFR-mutant Locally Advanced or Metastatic NSCLC

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Updated on 19 February 2024

Summary

A phase II study for locally advanced or metastatic non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) gene mutation, will test osimertinib with or without ramucirumab. Researchers hope to determine whether combining these drugs is better at controlling this type of cancer than osimertinib alone. To qualify, participants must be adults 18 or older and have locally advanced or metastatic NSCLC with EGFR.

Description

A phase II study for locally advanced or metastatic non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) gene mutation, will test osimertinib with or without ramucirumab. Researchers hope to determine whether combining these drugs is better at controlling this type of cancer than osimertinib alone. To qualify, participants must be adults 18 or older and have locally advanced or metastatic NSCLC with EGFR.

Details
Condition non-squamous,non-small cell lung cancer
Age 18years - 100years
Clinical Study IdentifierNCT03909334
Last Modified on19 February 2024

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