This study investigates the effectiveness and safety of a topical medication for individuals with open-angle glaucoma (OAG) or ocular hypertension (OHT). Open-angle glaucoma is a condition where the drainage angle for eye fluid remains open, but the fluid doesn't flow out as it should, increasing eye pressure. Ocular hypertension refers to higher than normal eye pressure without any optic nerve damage.

Participants in the study will receive a topical medication applied to the eye. The study will assess how long the medication lasts and its safety profile. No previous glaucoma surgeries are allowed for participants.

• Who can participate: Adults diagnosed with open-angle glaucoma or ocular hypertension in at least one eye are eligible to participate. Participants must require treatment to lower intraocular pressure and must not have had previous glaucoma eye surgery.
• Study details: Participants will apply a topical medication to their eye as part of the study. The study will evaluate how long the medication remains effective and monitor its safety. An inactive substance that looks like the investigational medication but does not contain any medicine may be used as a comparison.