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Randomized Double Blind Placebo Controlled Study of Erlotinib or Placebo in Patients With Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC)

Investigating the Effectiveness of Investigational Medication for Non-Small Cell Lung Cancer

Recruiting
18 years and older
All
Phase N/A

This study investigates the effectiveness of an investigational medication compared to a placebo in treating patients with stage IB-IIIA non-small cell lung cancer (NSCLC) that has been completely removed by surgery. Non-small cell lung cancer is a type of lung cancer that grows and spreads more slowly than small cell lung cancer. The study focuses on patients whose cancer has specific changes in the epidermal growth factor receptor (EGFR) gene, which can affect how cancer cells grow and divide.

Participants in this study will be randomly assigned to receive either the investigational medication or a placebo. A placebo is an inactive substance that looks like the investigational medicine but does not contain any medicine. The study will evaluate if taking the investigational medication after surgery and standard treatments can improve overall survival compared to taking a placebo.

  • Who can participate: Adults who have had surgery to completely remove stage IB-IIIA non-small cell lung cancer with certain EGFR mutations can participate. Participants must have a good performance status and have recovered from surgery and any required post-operative therapy. Specifically, participants must have an EGFR exon 19 deletion or L858R mutation.
  • Study details: Participants will be randomly assigned to receive either the investigational medication or a placebo.
Study details
    non-small cell lung cancer
    non small cell lung cancer
    non-small cell
    non small cell
    NSCLC
    lung cancer
    lung
    lungs
    cancer
    oncology

TX7270

19 February 2024

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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