A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-small Cell Lung Cancer: Crizotinib Versus Placebo for Patients With Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein

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Updated on 19 February 2024

Summary

This randomized phase III trial studies how well crizotinib works and compares it to placebo in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK).

Description

The purpose of this study is to evaluate whether adjuvant therapy with crizotinib will result in improved overall survival (OS) over placebo for patients with stage IB >= 4 cm, II and IIIA, ALK-positive non-small cell lung cancer (NSCLC) following surgical resection.

Participants will not be paid for their participation.

FAQ

Participants will not be paid for their participation.

Details
Condition Anaplastic Lymphoma Kinase,ALK,non-small cell lung cancer,non small cell lung cancer,non-small cell,non small cell,lung cancer,cancer,lung,lungs,oncology
Age 18years - 100years
Clinical Study IdentifierTX7271
Last Modified on19 February 2024

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