This study investigates how brain dopamine, a chemical in the brain, reacts when people smoke cigarettes. Dopamine is important for feelings of pleasure and reward. The study focuses on people who drink alcohol or smoke cigarettes to see how their brain reacts during smoking.
Participants will undergo imaging procedures to observe brain activity while smoking. Imaging procedures are tests that take pictures of the brain to see how it works. Participants will be compensated for their time and effort in the study.
- Who can participate: Healthy male and female cigarette smokers who are right-handed and can understand English are eligible. Participants must be daily smokers without neurological or medical disorders that could affect the study.
- Study details: Participants will undergo imaging procedures to observe brain activity while smoking. They must refrain from smoking on the day of the PET imaging study and should not have metal implants or other conditions that prevent MRI procedures.
- Study Timelines: The study will last approximately 10 hours over 2-3 days.
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