This study investigates the effects of two different approaches after surgery for grade II meningioma, a type of brain tumor. The purpose of this study is to compare the outcomes of observation alone versus radiation therapy following surgery. Participants will be randomly assigned to either continue with observation or receive radiation therapy, which involves the use of high-energy rays to target and kill cancer cells.
Participants who are assigned to the radiation therapy arm will receive treatment 5 days a week for approximately 6 1/2 to 7 weeks, totaling 33 treatments. All participants, regardless of their assigned arm, will have regular office visits and MRI scans to monitor their condition over time. MRI, or Magnetic Resonance Imaging, is a test that uses magnets and radio waves to take pictures of organs and structures inside the body.
- Who can participate: Adults aged 18 and older with a newly diagnosed grade II meningioma that has been completely removed through surgery are eligible. Individuals with prior invasive cancer, metastatic meningioma, or certain major medical illnesses are not eligible.
- Study details: Participants will be randomly assigned to one of two study arms: observation or radiation therapy. Radiation therapy involves receiving high-energy rays 5 days a week for about 7 weeks. All participants will have regular MRI scans, a type of imaging test, to monitor their condition. This study does not involve a placebo.
