Pilot Study of Cabozantinib for Recurrent or Progressive High-Grade Glioma in Children

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Updated on 19 February 2024

Summary

The purpose of this study is to find out if the drug, Cabozantinib, is safe and tolerable in pediatric patients with refractory and/or recurrent high grade gliomas (HGG) who have previously received radiation therapy. We are also looking to see if the drug has an effect on the rate at which the tumor grows at 6 months.

Description

The purpose of this study is to test the safety, tolerability and efficacy of carbozantinib in refractory and/or recurrent pediatric high-grade gliomas in children who have previously received radiation therapy.

Participants will not be paid for their participation.

FAQ

Participants will not be paid for their participation.

Details
Condition high-grade glioma,glioma,brain tumor,brain cancer,tumor,cancer,oncology,pediatric,riley,kid,kids,child,children,teen,teens,teenager,teenagers,youth,adolescent,childhood
Age 2years - 21years
Clinical Study IdentifierTX7541
Last Modified on19 February 2024

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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