Manually Controlled Infusion vs Target Controlled Infusion for StrokeThrombectomy (HASTE)

  • STATUS
    Recruiting
  • End date
    Oct 27, 2027
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Updated on 22 March 2026
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Accepts healthy volunteers

Summary

Brief Summary:
The goal of this randomized controlled trial is to compare manual general anesthesia induction to general anesthesia induction guided by target controlled infusion system in cerebral ischemic stroke
The main questions it aims to answer are:
  • Does target controlled infusion has a more favorauble hemodynamic profile than manual general anesthesia induction?
  • Do patients receiving general anesthesia with target controlled infusion system have a more favourable outcome? Participants will receive general anesthesia induction with a target controlled infusion system and will be compared to patients receiving manual general anesthesia induction.

Description

Study Type  :Interventional  (Clinical Trial)Estimated Enrollment  :224 participantsAllocation:RandomizedIntervention Model:Parallel AssignmentMasking:Double (Participant, Outcomes Assessor)Masking Description:Participants undergoing intervention will be unaware of the intervetion Outcomes assessor will be not involted in the other study of the study and will be not aware of the interventionPrimary Purpose:TreatmentOfficial Title:Manually Controlled Infusion vs Target Controlled Infusion: an Hemodynamic Alterations in StrokeThrombectomy Evaluation (HASTE); a Multi-center Randomized Controlled TrialEstimated Study Start Date  :October 15, 2022Estimated Primary Completion Date  :September 2024Estimated Study Completion Date  :December 2024

Details
Condition Acne
Age 100years or below
Clinical Study IdentifierTX112454
Last Modified on22 March 2026

Eligibility

 Yes No Not Sure

Inclusion Criteria

Age ≥ 18 years
Anterior Cerebral Circulation Stroke
Patient eligible for mechanical trombectomy
mRS ≥ 2
Fasting patients (>6 h solid, >2 hours liquids)
Glashow Coma Scale more than seven

Exclusion Criteria

Patient in general anesthesia at hospital arrival
Associated hemorrhagic stroke
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How to participate?

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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