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Multiple Phase 1 Safety Cohorts of Nivolumab Monotherapy or Nivolumab Combination Regimens Across Relapsed/Refractory Hematologic Malignancies

Study on the Safety of an Investigational Medication for Blood Cancers

Recruiting
18 years and older
All
Phase N/A

This study investigates the effectiveness, safety, and tolerability of an investigational medication for patients with relapsed or refractory blood cancers, which are also known as hematologic malignancies. These are cancers that affect the blood, bone marrow, and lymph nodes. The study aims to understand how well the medication works and how safe it is for patients.

Participants in the study will undergo various procedures to monitor their response to the investigational medication. These procedures will help researchers assess the medication's effectiveness and identify any potential side effects. Participants will be closely monitored throughout the study.

  • Who can participate: Adults with relapsed or refractory hematologic malignancies, who have a life expectancy of at least 3 months, and meet specific health criteria, such as adequate bone marrow, renal, and liver function, and an ECOG Performance status of 0 or 1, may be eligible. Participants must not have certain other health conditions or have received specific prior treatments.
  • Study details: Participants will receive either the investigational medication or a placebo. A placebo is an inactive substance that looks like the investigational medication but does not contain any medicine. The study will monitor the participants' health and response to the treatment.
Study details
    refractory
    relapsed
    hematologic malignancy
    malignancy
    hematologic
    oncology
    cancer

TX7675

19 February 2024

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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