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Virtual Reality Cognitive Intervention for Critically Ill Delirium Survivors (VR-Cog)

Virtual Reality Cognitive Intervention for Critically Ill Delirium Survivors (VR-Cog)

Recruiting
50 years and older
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

Acute respiratory failure (ARF) accounts for 2 million admissions to adult intensive care units (ICUs) in the United States annually, and up to 80% of older adults with ARF suffer delirium, a form of ICU-related acute brain dysfunction. Delirium doubles the risk for new cognitive impairment or dementia within 12 months of ICU discharge. In addition, delirium survivors frequently develop related mental health and quality of life impairments. Unfortunately, there are few effective or scalable interventions to improve cognitive outcomes for ICU survivors.

Primary Objective Aim 1: Measure the feasibility, acceptability, and adherence of VR-Cog in older adult ICU delirium survivors at risk for ICU-acquired MCI and ADRD.

Secondary Objective Aim 2: Estimate the effect of VR-Cog on cognitive performance among older adult ICU delirium survivors.

Tertiary/Exploratory/Correlative Objectives Aim 3: Explore the effects of VR-Cog on mental health (depression and anxiety).

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Study details
    Intensive Care Unit Delirium
    Intensive Care Acquired Cognitive Impairment
    Post Intensive Care Unit Syndrome
    Virtual Reality Cognitive Training

NCT07496255

Indiana University

20 August 2026

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