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A Pilot Study to assess Theragnostically Planned Liver Radiation with Functional DVH Analysis to Optimize Individualized Radiation Therapy

Investigating Radiation Treatment Plans for Liver Cancer

Recruiting
18 years and older
All
Phase N/A

The purpose of this study is to compare different radiation treatment plans for patients with liver cancer, such as hepatocellular carcinoma or cholangiocarcinoma. This study investigates whether adding specific imaging scans can help reduce radiation exposure to healthy liver tissue. A routine treatment plan will be compared with a plan that includes additional imaging using a HIDA scan and an MRI scan.

Participants will undergo two types of treatment planning. One will use the standard procedures, while the other will include extra imaging scans. The HIDA scan helps visualize liver function, and the MRI provides detailed images of liver structures. By comparing these plans, the study aims to determine if the additional scans can spare healthy liver tissue from radiation.

  • Who can participate: Adults with primary liver cancer, such as hepatocellular carcinoma or cholangiocarcinoma, and a Child-Turcotte-Pugh score of 7 or less may be eligible. Participants should not be pregnant or planning to become pregnant, and must have no more than 3 lesions with a total diameter of 6 cm or less. Previous radiation treatment to the upper abdomen and certain medical conditions may exclude participation.
  • Study details: Participants will undergo two radiation treatment planning sessions. One will use standard imaging techniques, while the other will include a HIDA scan and an MRI scan. The study will compare these plans to see if the additional scans reduce radiation to healthy liver tissue.
Study details
    liver cancer
    Hepatocellular Carcinoma
    Cholangiocarcinoma
    hepatic cancer
    hepatic
    liver
    radiation therapy
    radiation
    cancer
    oncology

TX7767

19 February 2024

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