A pilot phase 2 study evaluating dose de-escalation in whole brain radiation therapy with simultaneous integrated boost for patients with brain metastases

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Updated on 19 February 2024

Summary

This trial is a pilot, Phase 2, sequential two-cohort study designed to test two de-escalated whole brain radiation therapy (WBRT) dose levels and assess their ability to maintain acceptable in-brain distant control.

Description

The purpose of this study is to assess whole brain radiation therapy (known as WBRT) given with simultaneous higher dose radiation (known as SIB) targeted at individual brain tumors and the effects this treatment may have on the following areas: tumor control, memory, and specific thought processes.

Participants will not be paid for their participation.

FAQ

Participants will not be paid for their participation.

Details
Condition Cancer,Solid Tumor
Age 18years - 100years
Clinical Study IdentifierTX7933
Last Modified on19 February 2024

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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