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The Presence Study- Studying the Effect of LY3154207 on Cognition in Mild-to-Moderate Parkinson's Disease Dementia (PDD)

Investigational Medication for Memory and Thinking Problems in Parkinson's Disease Dementia

Recruiting
40-85 years
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates how an investigational medication compares with a placebo in treating memory and thinking problems in individuals with mild-to-moderate Parkinson's disease dementia. Parkinson's disease dementia (PDD) is a condition where people with Parkinson's disease experience a decline in cognitive functions, such as memory and thinking abilities, affecting their daily activities.

Participants will receive either the investigational medication or a placebo, which is an inactive substance that looks like the investigational medication but does not contain any medicine. The study will involve taking the medication daily for 12 weeks to observe any changes in cognitive function.

  • Who can participate: Adults with idiopathic Parkinson's disease for at least 2 years and experiencing dementia can participate. They must be on a stable dosage of medications affecting cognition and have a reliable caregiver for visits.
  • Study details: Participants will take either the investigational medication or a placebo daily for 12 weeks. A placebo is an inactive substance that looks like the investigational medication but does not contain any medicine. Participants must follow study rules, including not sharing personal medical data online.
  • Study Timelines and Visits: The study will last 12 weeks. The study requires 6 visits.
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Study details
    Parkinson's and memory
    Parkinson's dementia
    Parkinson's disease
    Parkinson's disease dementia

TX8499

19 February 2024

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