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Phase II Trial of Panitumumab Nivolumab and Ipilimumab for KRAS/NRAS/BRAF Wild-type MSS Refractory Metastatic Colorectal Adenocarcinoma

Study on the Safety and Anti-Cancer Activity of a 3-Drug Combination Therapy for Colorectal Cancer

Recruiting
18 years and older
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates the safety and anti-cancer effects of a combination of three investigational medications for colorectal cancer. Colorectal cancer is a type of cancer that starts in the colon or rectum. The study aims to understand how well these medications work together to fight this type of cancer.

Participants in the study will receive a combination of investigational medications. Some participants might receive a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine. The study will include monitoring of participants' health and response to the treatment.

  • Who can participate: Adults with confirmed metastatic or locally advanced colorectal adenocarcinoma can participate. Participants must have had 1-2 previous treatments, test negative for pregnancy, and agree to use contraception.
  • Study details: Participants will receive a combination of investigational medications or a placebo. A placebo is an inactive substance that looks like the investigational medicine but does not contain any medicine.
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Study details
    colon cancer

TX8762

19 February 2024

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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