This study investigates why some people often experience headaches after having a mild traumatic brain injury. A mild traumatic brain injury is a condition where the brain is affected by a sudden impact, but symptoms are not as severe as in more serious brain injuries. Researchers aim to understand whether factors like pain sensitivity, how the body adapts to pain, levels of inflammation in the blood, and changes in brain structure and function contribute to the risk of headaches.

Participants in this study will undergo various procedures to assess these factors. This may include blood tests to measure inflammation, tests to evaluate pain sensitivity, and possibly imaging to observe changes in brain structure and function. The study aims to gather data to better understand these associations.

• Who can participate: Adults in good health without a history of traumatic brain injury or chronic headaches are eligible. Those with chronic diseases, neurological, or psychiatric conditions are excluded.
• Study details: Participants will have blood tests, pain sensitivity assessments, and imaging studies to explore the link between mild traumatic brain injury and headaches.