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A Phase 2 Study of Neratinib with or without Fulvestrant in HER2-Positive ER-Positive Metastatic Breast Cancer

Study on Investigational Medication for Advanced Breast Cancer

Recruiting
18 years and older
Female
Phase N/A

This study investigates the effectiveness of an investigational medication, alone or in combination with another treatment, in treating breast cancer that has spread to other parts of the body. Breast cancer can be described as a disease where cells in the breast grow out of control, and when it spreads, it is known as metastatic breast cancer. The purpose of this study is to determine how well these treatments work and to observe any side effects that may occur.

Participants in this study will receive either the investigational medication alone or with another treatment. The study will monitor the effects of these treatments on breast cancer and assess any side effects. This will help researchers understand how the treatment impacts the disease.

  • Who can participate: Females aged 18 years or older with inoperable locally advanced or metastatic ER+ breast cancer are eligible to participate.
  • Study details: Participants will receive either the investigational medication alone or with another treatment. A placebo, an inactive substance that looks like the investigational medicine but does not contain any medicine, will not be used in this study.
Study details
    HER2
    metastatic breast cancer
    metastatic
    breast cancer
    cancer
    oncology

TX8968

19 February 2024

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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