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The CHEC-SC Cohort Study: CHaractErizing CFTR Modulated Changes in Sweat Chloride and their Association with Clinical Outcomes (the CHEC-SC study)

Investigation of Sweat Chloride Levels in Cystic Fibrosis Patients

Recruiting
1 years and older
All
Phase N/A

The purpose of this study is to investigate sweat chloride levels in patients with cystic fibrosis who are currently taking CFTR modulator therapies. Cystic fibrosis is a genetic condition that affects the lungs and digestive system, leading to the production of thick, sticky mucus. CFTR modulators are medications that help improve the function of the defective protein in cystic fibrosis patients.

Participants in this study will have their sweat chloride levels measured. Sweat chloride testing is a method used to diagnose cystic fibrosis and monitor treatment effectiveness. This study will involve collecting sweat samples from about 1000 patients who are taking CFTR modulators.

  • Who can participate: Individuals diagnosed with cystic fibrosis who have been on a prescribed CFTR modulator treatment for at least 3 months can participate. Participants must not be involved in any other investigational trials that might influence sweat chloride levels.
  • Study details: Participants will provide sweat samples for testing. The study will measure sweat chloride levels to understand the impact of CFTR modulators. No placebo is involved in this study.
Study details
    cystic fibrosis

TX9262

19 February 2024

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