This study is currently not recruiting participants.

A Phase III Randomized Trial of Adding Vincristine-topotecan-cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-metastatic Ewing Sarcoma

  • STATUS
    Not Recruiting
Updated on 19 February 2024

Summary

This randomized phase III trial studies combination chemotherapy to see how well it works compared to combination chemotherapy with topotecan hydrochloride in treating patients with non-metastatic extracranial Ewing sarcoma.

Description

The purpose of this study is to test the effect of the combination of vincristine (vincristine sulfate), cyclophosphamide, and topotecan (topotecan hydrochloride) (VTC) added to the standard 5-drug chemotherapy interval-compressed backbone on event-free and overall survival of children and young adults with Ewing sarcoma.

Details
Condition Ewing Sarcoma
Age 50years or below
Clinical Study IdentifierTX2029
Last Modified on19 February 2024

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