A Phase II Randomized Trial of Lenalidomide in Pediatric Patients with Recurrent Refractory or Progressive Juvenile Pilocytic Astrocytomas and Optic Pathway Gliomas
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- STATUS
- Not Recruiting
Summary
This randomized phase II trial studies how well low-dose lenalidomide works compared with high-dose lenalidomide in treating younger patients with juvenile pilocytic astrocytomas or optic nerve pathway gliomas that have come back (recurrent), have not responded to treatment (refractory), or are growing, spreading, or getting worse (progressive).
Description
The purpose of this study is to determine the objective response rate in children with recurrent, refractory, or progressive juvenile pilocytic astrocytomas and optic pathway gliomas who are treated with Regimen A low-dose (20 mg/m^2/dose) or Regimen B high-dose (115 mg/m^2/dose) lenalidomide.
Details
| Condition | Gliomas |
|---|---|
| Age | 21years or below |
| Clinical Study Identifier | TX2466 |
| Last Modified on | 19 February 2024 |
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