Phase II Study of Fosaprepitant + 5HT3 Receptor Antagonists + Dexamethasone in Patients With Germ Cell Tumors Undergoing 5 Day Cisplatin-based Chemotherapy: Hoosier Oncology Group Study QL12-153
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- STATUS
- Not Recruiting
Summary
The purpose of this study is to determine if EMEND, also known as fosaprepitant, can reduce sudden and delayed symptoms of nausea and vomiting in patients with germ cell cancer that are receiving standard treatment with a 5-day Cisplatin-based chemotherapy.
Description
The investigators propose to utilize intravenous (IV) fosaprepitant on days 3 and 5 of the 5-day cisplatin chemotherapy regimen. It is anticipated that fosaprepitant can suppress delayed chemo-induced nausea and vomiting for 2-5 days after therapy. This study will test the value of fosaprepitant in this patient population.
Details
| Condition | Germ Cell Tumor |
|---|---|
| Age | 15years - 100years |
| Clinical Study Identifier | TX2993 |
| Last Modified on | 19 February 2024 |
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