LCCC1227; Prospective Evaluation of the Effect of Curcumin on Dose-limiting Toxicity and Pharmacokinetics of Irinotecan in Colorectal Cancer Patients
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- STATUS
- Not Recruiting
Summary
The purpose of this study is to better understand the interaction between curcumin and irinotecan by measuring levels of irinotecan in the blood (ie. measure irinotecan PK) when a patient also takes curcumin.
Description
This is a single-center, two-part, open label prospective study to define the maximum tolerated dose (MTD) of curcumin plus irinotecan and the pharmacokinetic effects of curcumin on irinotecan metabolism in patients with advanced colorectal cancer.
Details
| Condition | Colorectal Cancer |
|---|---|
| Age | 21years - 100years |
| Clinical Study Identifier | TX4239 |
| Last Modified on | 19 February 2024 |
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