This study is currently not recruiting participants.

ADVL1411; A Phase 1/2 Study of BMN 673 an Oral Poly(ADP-Ribose) Polymerase Inhibitor Plus Temozolomide in Children With Refractory or Recurrent Malignancies

  • STATUS
    Not Recruiting
Updated on 19 February 2024

Summary

This phase I/II trial studies the side effects and best dose of talazoparib and temozolomide and to see how well they work in treating younger patients with tumors that have not responded to previous treatment (refractory) or have come back (recurrent).

Description

The purpose of this study is to test the experimental drug combination of BMN 673 and temozolomide in the hopes of finding a treatment that may be effective against tumors that have come back or that have not responded to standard therapy.

Details
Condition Cancer
Age 1years - 30years
Clinical Study IdentifierTX4710
Last Modified on19 February 2024

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