This study investigates Alzheimer’s disease, other memory and thinking disorders, and normal memory and thinking in older individuals. Alzheimer’s disease is a condition that affects memory, thinking, and behavior. The study aims to understand these conditions better by observing different groups of people.

Participants will undergo evaluations and assessments to study their memory and thinking abilities. These procedures will help researchers gather information about how memory and thinking disorders affect individuals over time.

• Who can participate: Adults with normal cognition or mild to moderate memory problems can participate. Participants need a study partner, a relative or friend of at least 10 years, to assist during study visits. Participants should not be pregnant, nursing, have major medical or psychiatric conditions, or be claustrophobic.
• Study details: Participants will be evaluated on their memory and thinking abilities with the help of a study partner who can provide information about their memory during visits. A placebo may be used in the study for comparative purposes.