Hypothermia's Impact on Pharmacology
-
- STATUS
- Not Recruiting
Summary
The purpose of this study is to identify the physiologic manifestations of cardiac arrest and multi organ dysfunction syndrome (MODS) that underlie the variability in morphine and midazolam pharmacokinetics; to estimate the impact of genetic factors on the variability in morphine and midazolam pharmacokinetics, specifically in the setting of pediatric cardiac arrest; and to estimate the impact of hypothermia on the variability in morphine and midazolam pharmacokinetics in children after cardiac arrest.
Description
The purpose of this study is to identify the physiologic manifestations of cardiac arrest and multi organ dysfunction syndrome (MODS) that underlie the variability in morphine and midazolam pharmacokinetics; to estimate the impact of genetic factors on the variability in morphine and midazolam pharmacokinetics, specifically in the setting of pediatric cardiac arrest; and to estimate the impact of hypothermia on the variability in morphine and midazolam pharmacokinetics in children after cardiac arrest.
Details
| Condition | cardiac arrest |
|---|---|
| Age | 100years or below |
| Clinical Study Identifier | TX6492 |
| Last Modified on | 19 February 2024 |
Similar trials to consider
Not finding what you're looking for?
Sign up as a volunteer to stay informed
Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.
Sign up as volunteerStudy Definition
WikipediaAdd a private note
- Select a piece of text.
- Add notes visible only to you.
- Send it to people through a passcode protected link.