A Phase II Study of Cabozantinib (XL184) for Plexiform Neurofibromas in Subjects With Neurofibromatosis Type 1 in Children and Adults

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Updated on 19 February 2024

Summary

The purpose of this Phase II Study is to determine the response rate of NFI patients with plexiform neurofibromas treated with Cabozantinib therapy using MRI scans.

Description

This phase II open label study will evaluate adolescents and adults with neurofibromatosis type-1 (NF1) and plexiform neurofibromas treated with cabozantinib (XL184).

Participants will not be paid for their participation.

FAQ

Participants will not be paid for their participation.

Details
Condition Neurofibromatosis Type 1,Plexiform Neurofibromas,Neurofibromatosis Type 1,Neurofibromatosis Type I,Plexiform Neurofibroma,Neurofibroma,Neurofibromas,Neurofibromatosis
Age 3years - 100years
Clinical Study IdentifierTX3396
Last Modified on19 February 2024

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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