Concordance of sensitivity and resistance testing between Cisplatin and Ifosfamide in Soft Tissue Sarcomas: A Retrospective Review
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- STATUS
- Not Recruiting
Summary
This study is as a retrospective database including clinical information from patients with soft tissue sarcomas seen at IUSCC during the period June 2010 ? June 2012 and treated with the specific chemotherapy agents, Cisplatin and Ifosfamide. Researchers propose to perform a retrospective record review of adult patients who had cisplatin and Ifosfamide sensitivity and resistance testing by Precision Therapeutics laboratory (Pittsburgh, PA). Researchers will determine whether there are perhaps 2 or 3 histologic subtypes of soft tissue sarcoma that are more likely to be sensitive or resistant to cisplatin. Researchers will record whether the patients ever received cisplatin or ifosfamide from June 2010 through June 2012 for the treatment of soft tissue sarcoma. Toxicity and response will be assessed in patients who were tested for cisplatin or ifosfamide sensitivity. Researchers will also determine if there was correlation of clinical response with laboratory live tissue testing.
Description
This study is as a retrospective database including clinical information from patients with soft tissue sarcomas seen at IUSCC during the period June 2010 ? June 2012 and treated with the specific chemotherapy agents, Cisplatin and Ifosfamide. Researchers propose to perform a retrospective record review of adult patients who had cisplatin and Ifosfamide sensitivity and resistance testing by Precision Therapeutics laboratory (Pittsburgh, PA). Researchers will determine whether there are perhaps 2 or 3 histologic subtypes of soft tissue sarcoma that are more likely to be sensitive or resistant to cisplatin. Researchers will record whether the patients ever received cisplatin or ifosfamide from June 2010 through June 2012 for the treatment of soft tissue sarcoma. Toxicity and response will be assessed in patients who were tested for cisplatin or ifosfamide sensitivity. Researchers will also determine if there was correlation of clinical response with laboratory live tissue testing.
Details
| Condition | soft tissue sarcoma |
|---|---|
| Age | 100years or below |
| Clinical Study Identifier | TX7261 |
| Last Modified on | 19 February 2024 |
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