A Randomized Phase II Study of Perioperative mFOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel as Therapy for Resectable Pancreatic Adenocarcinoma
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- STATUS
- Not Recruiting
Summary
This randomized phase II trial studies how well fluorouracil, irinotecan hydrochloride, and oxaliplatin (combination chemotherapy) works and compares to gemcitabine hydrochloride and paclitaxel albumin-stabilized nanoparticle formulation before surgery in treating patients with pancreatic cancer that can be removed by surgery.
Description
The purpose of this study is to assess 2-year overall survival in each treatment arm (fluorouracil, irinotecan hydrochloride, and oxaliplatin [modified (m)FOLFIRINOX] and gemcitabine [gemcitabine hydrochloride]/nab-paclitaxel [paclitaxel albumin-stabilized nanoparticle formulation]) in patients with resectable pancreatic cancer; and if the stated threshold is met in one or both arms: to choose the better regimen with respect to 2-year overall survival.
Details
| Condition | pancreatic cancer |
|---|---|
| Age | 18years - 75years |
| Clinical Study Identifier | TX8338 |
| Last Modified on | 19 February 2024 |
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