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Early ADRD Detection

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Updated on 19 February 2024

Summary

Using the data infrastructure of both the INPC and SECBC, we are proposing to conduct a 10 year retrospective cohort study to accomplish the following aims:

Specific Aim 1: Use the INPC structured data to develop a multivariable, validated and scalable model to identify the 5 and 10-year early prodromal ADRD signatures.

Specific Aim 2: Use the INPC structured and unstructured data via natural language processing to develop a multivariable, validated and scalable model to identify the 5 and 10-year early prodromalADRD signatures.

Specific Aim 3: Use the INPC structured and structured data and the patient and informal caregiver reported symptoms from the SECBCI data to develop a multivariable, validated and scalable model to identify the 5-year early prodromal ADRD signatures.

Description

Using the data infrastructure of both the INPC and SECBC, we are proposing to conduct a 10 year retrospective cohort study to accomplish the following aims:

Specific Aim 1: Use the INPC structured data to develop a multivariable, validated and scalable model to identify the 5 and 10-year early prodromal ADRD signatures.

Specific Aim 2: Use the INPC structured and unstructured data via natural language processing to develop a multivariable, validated and scalable model to identify the 5 and 10-year early prodromalADRD signatures.

Specific Aim 3: Use the INPC structured and structured data and the patient and informal caregiver reported symptoms from the SECBCI data to develop a multivariable, validated and scalable model to identify the 5-year early prodromal ADRD signatures.

Details
Condition Alzheimer's Disease,dementia
Age 100years or below
Clinical Study IdentifierTX8370
Last Modified on19 February 2024

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