Genomics of Pulmonary Vascular Disease: existing de-identified samples.
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- STATUS
- Not Recruiting
Summary
The purpose of this study is to identify inherited genetic changes that predispose to PAH, heart defects, or HHT; to understand the role of DNA damage, which can lead to additional genetic changes acquired during a person's lifetime, and may contribute to disease risk; to determine if increased levels of DNA damage can identify the persons with a heart defect who are at highest risk for developing PAH; and to identify novel therapies that correct the biochemical defects underlying PAH and HHT.
Description
The purpose of this study is to identify inherited genetic changes that predispose to PAH, heart defects, or HHT; to understand the role of DNA damage, which can lead to additional genetic changes acquired during a person's lifetime, and may contribute to disease risk; to determine if increased levels of DNA damage can identify the persons with a heart defect who are at highest risk for developing PAH; and to identify novel therapies that correct the biochemical defects underlying PAH and HHT.
Details
| Age | 100years or below |
|---|---|
| Clinical Study Identifier | TX8597 |
| Last Modified on | 19 February 2024 |
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