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Long Term Outcomes of Ventricular Pacing in Single Ventricle Congential Heart Disease - A Multicenter International Study

  • STATUS
    Not Recruiting
Updated on 19 February 2024

Summary

The purpose of this study is to:
1. To assess morbidity and mortality in ventricularly paced single ventricle congenital heart disease (CHD) patients, using a primary endpoint of heart transplantation or death, and the secondary endpoints of moderate-severe ventricular dysfunction and atrioventricular valvar regurgitation (AVVR), as compared to age, gender and type of single ventricle matched controls. 2. To determine the patient characteristics that predispose a single ventricle CHD patient requiring ventricular pacing to a higher risk of heart transplantation or death, and the development of moderate-severe ventricular dysfunction and AVVR. 3. To determine the association of mechanical dyssynchrony indices to pacing lead location in a subset of ventricularly paced Fontan patients, as compared to age, gender and type of single ventricle matched controls.

Description

The purpose of this study is to:
1. To assess morbidity and mortality in ventricularly paced single ventricle congenital heart disease (CHD) patients, using a primary endpoint of heart transplantation or death, and the secondary endpoints of moderate-severe ventricular dysfunction and atrioventricular valvar regurgitation (AVVR), as compared to age, gender and type of single ventricle matched controls. 2. To determine the patient characteristics that predispose a single ventricle CHD patient requiring ventricular pacing to a higher risk of heart transplantation or death, and the development of moderate-severe ventricular dysfunction and AVVR. 3. To determine the association of mechanical dyssynchrony indices to pacing lead location in a subset of ventricularly paced Fontan patients, as compared to age, gender and type of single ventricle matched controls.

Details
Condition Single Ventricle Congential Heart Disease
Age 100years or below
Clinical Study IdentifierTX8667
Last Modified on19 February 2024

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