This study investigates the effects of weight loss after bariatric surgery on breast cancer biomarkers and breast density. Biomarkers are substances in the body that can indicate a disease or condition, and breast density refers to the amount of fibrous or glandular tissue compared to fatty tissue in the breasts. The study focuses on women who are at an elevated risk for breast cancer.
Participants will undergo procedures including a core tissue biopsy, which involves taking a small sample of breast tissue for testing. This will happen at the start of the study, and again two weeks and twelve months after the surgery. Blood samples and imaging tests will also be conducted to observe changes in breast cancer risk factors.
- Who can participate: Women who are at an elevated risk for breast cancer and are planning to undergo primary bariatric surgery can participate. Participants must be willing to provide tissue samples, meet specific health criteria, and have no known allergies or weight limitations that could affect the study.
- Study details: Participants will provide tissue samples and undergo imaging tests. A placebo is not used in this study.
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