Retrospective Review of Pediatric Patients with Intestinal Failure to Determine Predictors of Intestinal Failure Other Organ Failure and Clinical Outcomes
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- STATUS
- Not Recruiting
Summary
Children with loss of the intestine, or severe dysfunction of the intestine, require intravenous feedings known as parenteral nutrition. Long-term parenteral nutrition results in multiple complications including recurrent sepsis, liver failure, kidney failure and loss of intravenous access. One option for definitive treatment for these children is intestinal transplantation. However, the timing of intestinal transplantation is critical. Some children can develop adequate intestinal function and do not need transplantation. However, if transplantation is not performed in a timely fashion, the child may develop liver failure and need combined liver and intestinal transplant or may die from complications. This study is a retrospective data collection and analysis project designed to determine clinical predictors of organ failure in children with intestinal failure and parenteral nutrition dependence.
Description
Children with loss of the intestine, or severe dysfunction of the intestine, require intravenous feedings known as parenteral nutrition. Long-term parenteral nutrition results in multiple complications including recurrent sepsis, liver failure, kidney failure and loss of intravenous access. One option for definitive treatment for these children is intestinal transplantation. However, the timing of intestinal transplantation is critical. Some children can develop adequate intestinal function and do not need transplantation. However, if transplantation is not performed in a timely fashion, the child may develop liver failure and need combined liver and intestinal transplant or may die from complications. This study is a retrospective data collection and analysis project designed to determine clinical predictors of organ failure in children with intestinal failure and parenteral nutrition dependence.
Details
| Age | 100years or below |
|---|---|
| Clinical Study Identifier | TX9141 |
| Last Modified on | 19 February 2024 |
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