Diabetes Mellitus, Type 1 Clinical Trials

Targeting Polyamines using DFMO in Persons with Type 1 Diabetes: A Randomized Double-Masked Placebo-Controlled Phase I/II Study to Evaluate the Safety Tolerability and Initial Pharmacodynamics of Multiple Ascending Doses

The purpose of this study is to determine if different doses of a drug known as DFMO have an effect on reducing the amount of stress that is experienced by the body's beta cells and preserves residual c-peptide.

Identification of Serum and Urine Biomarkers of Type 1 Diabetes

The purpose of this study is to identify biomarkers (small molecules in the blood) that can predict those people at risk of developing Type 1 diabetes.

Open-label, single-arm, multiple-dose safety, titration, and pharmacokinetic study of AFREZZA® in pediatric subjects ages 4 to 17 years with type 1 diabetes mellitus

The purpose of this research study is to measure how much of the study drug (Afrezza) gets into your bloodafter a single dose and measure how well it works to control your blood sugar level. We also want to make surethis study drug is safe for children and adolescents between …

A Prospective Randomized, Double-Blind Comparison of LY900014 to Humalog with an Open-Label Postprandial LY900014 Treatment Group in Children and Adolescents with Type 1 Diabetes PRONTO-Peds

  The main reason for you to take part in this study is not to treat you for your diabetes but to help in answering the following research questions: •Does LY900014 help to lower blood glucose levels in patients with type 1 diabetes? •How LY900014 controls blood glucose levels compared …

A phase 3 randomized double-blind placebo- and active-controlled parallel-arm trial to assess the efficacy safety and pharmacokinetics of dasiglucagon relative to placebo and GlucaGen? when administered as a rescue therapy for severe hypoglycemia in children with T1DM treated with insulin

This study will compare medications used to treat low blood sugars (hypoglycemia).

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