Tumor Clinical Trials
A listing of Tumor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 194 clinical trials
DREAMseq (Doublet, Randomized Evaluation in Advanced Melanoma Sequencing) a Phase III Trial
This randomized phase III trial studies how well initial treatment with ipilimumab and nivolumab followed by dabrafenib and trametinib works and compares it to initial treatment with dabrafenib and trametinib followed by ipilimumab and nivolumab in treating patients with stage III-IV melanoma that contains a mutation known as v-raf murine …
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- 19 Feb, 2024
- 1 location
A Study Evaluating the Pregnancy Outcomes and Safety of Interrupting Endocrine Therapy for Young Women With Endocrine Responsive Breast Cancer Who Desire Pregnancy (IBCSG48-POSITIVE)
The aim of the study is to investigate if temporary interruption of endocrine therapy, with the goal to permit pregnancy, is associated with a higher risk of breast cancer recurrence. The study aims also to evaluate different specific indicators related to fertility, pregnancy and breast cancer biology in young women.
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- 19 Feb, 2024
- 1 location
Tomosynthesis Mammographic Imaging Screening Trial (TMIST)
This randomized phase III trial studies digital tomosynthesis mammography and digital mammography in screening patients for breast cancer.
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- 19 Feb, 2024
- 1 location
Effects of Modern Chemotherapy Regimens on Spermatogenesis and Steroidogenesis in Adolescent and Young Adult (AYA) Survivors of Osteosarcoma
This research trial studies saliva, semen, and blood samples to determine effects of chemotherapy on fertility in osteosarcoma survivors. Study biospecimen samples from osteosarcoma survivors in the laboratory may help doctors learn whether chemotherapy causes fertility problems and to learn more about the long term effects.
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- 19 Feb, 2024
- 1 location
Phase II Trial of Atezolizumab in BCG-Unresponsive Non-muscle Invasive Bladder Cancer
This phase II trial studies how well atezolizumab works in treating patients with non-muscle invasive bladder cancer that has come back and has not responded to treatment with Bacillus Calmette-Guerin (BCG).
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- 19 Feb, 2024
- 1 location
A Phase II Study of Combining Talimogene Laherparepvec T-VEC (NSC-785349) and MK-3475 (Pembrolizumab) (NSC-776864) in Patients With Advanced Melanoma Who Have Progressed on Anti-PD1/L1 Based Therapy
The purpose of this study is to test any good and bad effects of the combination of study drugs called MK-3475 (pembrolizumab) and talimogene laherparepvec (T-VEC) in melanoma patients.
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- 19 Feb, 2024
- 1 location
A Phase Ib/II Clinical Study of BBI608 Administered With Paclitaxel in Adult Patients With Advanced Malignancies
This is an open label, single arm phase 1 dose escalation study and phase 2 study of BBI608 in combination with paclitaxel in patients with advanced malignancies.
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- 19 Feb, 2024
- 1 location
Total Cancer Care: A Lifetime Partnership with Patients Who Have or May be at Risk of Having Cancer
This research study is to build a large database (of information and specimens) to find better ways to prevent, diagnose and treat cancer.
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- 19 Feb, 2024
- 1 location
A Randomized Phase III Trial to Evaluate the Efficacy and Safety of MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer With ? 1 CM Residual Invasive Cancer or Positive Lymph Nodes (ypN+) After Neoadjuvant Chemotherapy
This randomized phase III trial studies how well pembrolizumab works in treating patients with triple-negative breast cancer.
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- 19 Feb, 2024
- 1 location
RADY-GU-SAYKIN-TLC; Older breast cancer patients: Risk for cognitive decline
We are looking for healthy women (who have never had cancer) to participate in a study of at Indiana University School of Medicine. We are working to better understand cognitive changes after breast cancer treatment.
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- 19 Feb, 2024
- 1 location