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Found 511 clinical trials

Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)

This research trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery.

18 years and older
All
Phase N/A

Randomized Double Blind Placebo Controlled Study of Erlotinib or Placebo in Patients With Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC)

This randomized phase III trial studies how well erlotinib hydrochloride compared to placebo works in treating patients with stage IB-IIIA non-small cell lung cancer that has been completely removed by surgery.

18 years and older
All
Phase N/A

A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-small Cell Lung Cancer: Crizotinib Versus Placebo for Patients With Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein

This randomized phase III trial studies how well crizotinib works and compares it to placebo in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK).

18 years and older
All
Phase N/A

Adjuvant Nivolumab in Resected Lung Cancers (ANVIL) - A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-small Cell Lung Cancers

This randomized phase III trial studies how well nivolumab after surgery and chemotherapy work in treating patients with stage IB-IIIA non-small cell lung cancer.

18 years and older
All
Phase N/A

The temporal stability of conditioned pain modulation and temporal summation of pain among healthy adults

The purpose of this study is to determine how consistently and reliably people are able to distinguish among levels of pain they experience in order to improve the treatment of pain.

18-40 years
All
Phase N/A

A Study to Assess the Effect of Y-90 Therapy on Non-target/Background Liver

The primary question of interest is quantifying the relationship between Y-90 liver therapy and liver damage.

18 years and older
All
Phase N/A

Functional Screening Tests for Predicting Injury in Ballet Dancers

This research will be conducted to examine the various functional tests that are used when screening ballet dancers before a season, in order to determine if they have the ability to predict if a dancer will suffer an injury or injuries. The goal of this research is to identify the …

18-30 years
All
Phase N/A

A Randomized Phase III Double Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for Node Positive HER2 Negative Breast Cancer: The ABC Trial

This randomized phase III trial studies how well aspirin works in preventing the cancer from coming back (recurrence) in patients with human epidermal growth factor receptor 2 (HER2) breast cancer after chemotherapy, surgery, and/or radiation therapy.

18-69 years
All
Phase N/A

A Phase 1 Study to Evaluate the Safety and Tolerability of a Study Drug in Subjects with Early Alzheimer's Disease (AD)

This study will test the safety and tolerability of an experimental study drug that may delay Alzheimer’s disease (AD) onset or slow the progression of possible AD-related damage due to protein build-up in the brain.   Methods include measuring the amount of study drug and drug-related material in the cerebrospinal fluid …

55-85 years
All
Phase 1

Dopamine and Smoking Behaviors

The purpose of this study is to understand how and where brain dopamine reacts while you smoke a cigarette.

18-55 years
All
Phase N/A

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