Found 511 clinical trials
A Phase 1 Study of ABI-009 (NAB-RAPAMYCIN) in Pediatric Patients With Recurrent or Refractory Solid Tumors Including CNS Tumors as a Single Agent and in Combination With Temozolomide and Irinotecan
This phase I trial studies the side effects and best dose of nanoparticle albumin-bound rapamycin when given together with temozolomide and irinotecan hydrochloride in treating pediatric patients with solid tumors that have come back after a period of time during which the tumor could not be detected or has not …
Phase I/II Trial Evaluating Five Fraction SABR Dose Escalation for Early Stage Squamous Cell Carcinoma of the Lung
The purpose of this study is to test whether 5 fraction stereotactic ablative body radiation (SABR) is safe and improves local control for early state squamous cell carcinoma of the lung.
Reduced Intensity Conditioning for Haploidentical Bone Marrow Transplantation in Patients with Symptomatic Sickle Cell Disease
We're doing this study to learn if a haploidentical transplant is safe and effective to treat SCD.
Ultrasound study of tongue shape and position in speech sound production
The purpose of this study is to determine the position and configuration of the tongue in the production of various speech sounds by native speakers of the investigated language.
Evaluation of the Mandarin Gratitude Group Program in comparison with the Wellness Group
The purpose of this study is to provide a research evaluation of a six-week Mandarin group program designed to cultivate personal growth and wellness.
COLLECTION OF SPECIMENS AND CLINICAL DATA TO CREATE A BIOREPOSITORY AND REGISTRY FOR INFLAMMATORY BREAST CANCER
The purpose of this study is to collect inflammatory breast cancer specimens. Researchers will look at differences between specimens. They will study the disease development with the goal of improving ways to prevent, diagnose and treat inflammatory breast cancer.
A Study Evaluating the Pregnancy Outcomes and Safety of Interrupting Endocrine Therapy for Young Women With Endocrine Responsive Breast Cancer Who Desire Pregnancy (IBCSG48-POSITIVE)
The aim of the study is to investigate if temporary interruption of endocrine therapy, with the goal to permit pregnancy, is associated with a higher risk of breast cancer recurrence. The study aims also to evaluate different specific indicators related to fertility, pregnancy and breast cancer biology in young women.
International Phase 3 Trial in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ALL) Testing Imatinib in Combination With Two Different Cytotoxic Chemotherapy Backbones
This randomized phase III trial studies how well imatinib mesylate and combination chemotherapy work in treating patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukemia.
A Multicenter Randomized Double Blind Placebo Controlled Parallel Group Pilot Study to Assess the Efficacy and Safety of H.P. Acthar Gel in Subjects with Relapsing-remitting Multiple Sclerosis
The purpose of this study is to examine the safety, tolerability and response rate of Acthar in subjects with RRMS who have not responded to high dose intravenous methylprednisolone (IVMP), oral prednisone, or oral methylprednisolone.
Multisensory processing in the elderly
This research is being done to investigate multisensory processing in young and older adults.
