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Found 511 clinical trials

A First-in-Human Phase I Trial to Determine the Safety and the Pharmacokinetic Profile of DSP-0509 a Synthetic Toll-Like Receptor 7 (TLR-7) Agonist in Adult Patients With Advanced Solid Tumors

This is a Phase 1, open label, multi-center study of intravenously administered DSP-0509 in adult subjects with advance solid tumors that are refractory to standard treatment.

18 years and older
All
Phase N/A

Functional and Neurochemical Substrates of Chemotherapy-Related Cognitive Deficits

The purpose of this study is to understand how chemotherapy alters brain function and brain chemistry.

19-55 years
Female
Phase N/A

Biodistribution and dosimetry of the investigational PET agent 68Ga-P16-093 in prostate cancer patients with biochemical recurrence undergoing clinical 68Ga-PSMA-11 PET/CT

Whole body biodistribution and dosimetry with preliminary comparison to PSMA-11 in prostate cancer patients with biochemical recurrence

18 years and older
Male
Phase N/A

A Phase II trial of Atezolizumab (anti-PDL1) with Carboplatin in Patients with Metastatic Triple Negative Breast Cancer

The purpose of this study is to test how well the combination of study drugs, carboplatin and atezolizumab, keeps metastatic triple negative breast cancer from growing compared to taking carboplatin only.

18 years and older
All
Phase N/A

Neural and Cognitive Bases of Language Processing

Purdue Aphasia Research Lab invites healthy older adults and individuals with stroke-induced aphasia to participate in a NIH-funded research project. The goal of the project is to examine how different types of cues facilitate sentence production and comprehension in persons with aphasia. The findings will lead to development of more …

30-85 years
All
Phase N/A

A Phase 1/2 Trial of VX15/2503 in Children Adolescents or Young Adults With Recurrent or Relapsed Solid Tumors

This phase I/II trial studies the side effects and best dose of anti-SEMA4D monoclonal antibody VX15/2503 (VX15/2503) and to see how well it works in treating younger patients with solid tumors that have come back after treatment, or do not respond to treatment.

1-30 years
All
Phase N/A

Dietary Nitrate and Muscle Power with Aging

The purpose of this study is to see if drinking beetroot juice (BRJ) is beneficial for aging subjects.

65-79 years
All
Phase N/A

How Learning is Influenced by Trait Competitiveness and Self-Efficacy in a Multi-phase Competition

The purpose of this study is to discover how personality types may affect someone?s ability to learn and improve themselves. Specifically, learn and improve in a competition.

18 years and older
All
Phase N/A

[RL-Diss] First and Second Language Listening Comprehension and RLS Effects

The purpose of this study is to examine the factors that contribute to greater or less success in listening comprehension for first and second language listeners. We are particularly interested in the effect of different speakers, and of your memory span on comprehension. The goal is to understand how people …

18-30 years
All
Phase N/A

Physiological Correlates of Shyness

We are trying to determine the relationship between personality processes and psychophysiological activity, including such basic measures as hand temperature, skin moisture, heart rate, and respiration rate.

18 years and older
All
Phase N/A

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