Found 511 clinical trials
A Phase 1b/2a Multi-Center Open-Label Study to Evaluate the Safety and Efficacy of Combination Treatment with MEDI0457 (INO-3112) and Durvalumab (MEDI4736) in Patients with Recurrent/Metastatic Human Papilloma Virus Associated Head and Neck Squamous Cancer
The purpose of this research study is to measure how well and how safe MEDI0457 vaccine in combination with Durvalumab is in treating patients with recurrent/metastatic human papilloma virus associated head and neck squamous cancer.
STEPS to Enhance Physical Activity (STEPS) after Hematopoietic Stem Cell Transplantation (HCT) for Multiple Myeloma
The purpose of this pilot study is to test the preliminary effects of a free-living physical activity intervention, STEPS to Enhance Physical Activity (STEPS), compared to usual care on fatigue (tiredness), functional ability (ability to perform tasks associated with daily living, like moving from a sitting to standing position), muscle …
Dissecting the Genetic Contributions to Fetal Alcohol Spectrum Disorders (DiG FASD)
The purpose of the “Dissecting the Genetic Contributions to Fetal Alcohol Spectrum Disorders” (DiG FASD) study is to understand how genetics affects FASD.
Womens descent into drugs and crime
The purpose of this project is to explore the circumstances and life events that influence women down the path of drug use and criminal activity.
Training to Reconnect With Emotional Awareness Therapy (TREAT)
The purpose of this study is to help healthcare professionals better understand traumatic brain injury and the management of emotional problems. The purpose of this study is to examine how treatment program changes participants awareness and understanding of their emotions, and ability to control their emotions.
Adult life for individuals with Down syndrome
The purpose of this study is to explore the current experiences and quality of life for adults with Down syndrome as perceived by themselves, their family members, and direct support professionals.
Phase II Trial of Panitumumab Nivolumab and Ipilimumab for KRAS/NRAS/BRAF Wild-type MSS Refractory Metastatic Colorectal Adenocarcinoma
The purpose of this research study is to learn more about the safety and anti-cancer activity of a 3-drug combination therapy involving antibodies nivolumab, ipilimumab and panitumumab.
A Phase II Randomized Open label Study of High Dose Interleukin 2 vs High Dose Interleukin 2 plus Entinostat in Untreated Advanced Renal Cell Carcinoma (GU17-289)
The purpose of this study is to compare any good and bad effects of using a high dose Interleukin (IL-2) and Entinostat to using IL-2 alone. The addition of Entinostat to high dose IL-2 could shrink your cancer/prevent it from returning for a longer period of time but it could …
A Phase 3 Randomized Study Comparing Perioperative Nivolumab vs. Observation in Patients With Localized Renal Cell Carcinoma Undergoing Nephrectomy (PROSPER RCC)
This randomized phase III trial compares nephrectomy (surgery to remove a kidney or part of a kidney) with or without nivolumab in treating patients with kidney cancer that is limited to a certain part of the body (localized).
Individual differences in the perception of regional dialects
This study will investigate the perception of regional dialects including listeners' abilities to classify the dialects into groups and rate speakers from various dialect regions in a language attitudes task.
