Found 511 clinical trials
A Randomized Phase II Study of Nivolumab After Combined Modality Therapy (CMT) in High Risk Anal Cancer
This randomized phase II clinical trial studies how well nivolumab after combined modality therapy works in treating patients with high risk stage II-IIIB anal cancer.
Understanding of Social Camouflage through Monikers in Video Games and Gaming Communities
Although many people are not able to entirely choose the names they use in day-to-day life, they are able to choose the names they go by online. In the context of gaming, this might mean your in -game username or gamertag as well as names you use on gaming forums, …
Modeling neural structure-function relationships and identifying neural predictors of cognitive-linguistic ability in older adults and stroke survivors
The purpose of this study is to examine the brain?s organization of structure (how the brain looks) and function (how areas of the brain interact with each other) and how this relates to cognition. Specifically, we are interested in how brain anatomy and its related functions are associated with cognitive-linguistic …
Study of Mathematical Learning in Children
The purpose of this study is to investigate mathematical and number processing.
A Phase 3 Open-label Rollover Study to Evaluate the Safety and Efficacy of Long-term Treatment With Tezacaftor in Combination With Ivacaftor in Subjects With Cystic Fibrosis Aged 6 Years and Older Homozygous or Heterozygous for the F508del-CFTR Mutation
The purpose of this study is to evaluate the long-term safety and tolerability of TEZ/IVA in subjects with cystic fibrosis aged 6 years and older, who are homozygous or heterozygous for F508del mutation.
A Phase 3 2-part Open-label Study to Evaluate the Safety and Pharmacokinetics of Lumacaftor/Ivacaftor in Subjects 1 to Less Than 2 Years of Age With Cystic Fibrosis Homozygous for F508del
This study is being done to learn more about the safety and effects of the combination of Lumacaftor (LUM) and Ivacaftor (IVA) in patients with Cystic Fibrosis between 1 to less than 2 years of age.
An Open-label Multicenter Phase 2 Study Evaluating the Efficacy and Safety of Daratumumab in Pediatric and Young Adult Subjects >=1 and =30 Years of Age With Relapsed/Refractory Precursor B-cell or T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
The purpose of this study is to see if Daratumumab is useful for treating pediatric (subjects aged >=1 to 18 years) and young adult patients (aged 18 to 30 years) with acute lymphoblastic leukemia or lymphoblastic lymphoma.
Randomized Trial of Standard Chemotherapy Alone or Combined With Atezolizumab as Adjuvant Therapy for Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair
This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair.
A Non-randomized Open-label Multi-center Phase I/II Study of Phosphatidylinositol-3-kinase (PI3K) Inhibitor Copanlisib in Pediatric Patients With Relapsed/Refractory Solid Tumors or Lymphoma
This study is designed to investigate whether the use of copanlisib is safe, feasible and beneficial to pediatric patients with solid solid tumors or lymphoma that are recurrent or refractory to standard therapy.
A phase 3 randomized double-blind placebo- and active-controlled parallel-arm trial to assess the efficacy safety and pharmacokinetics of dasiglucagon relative to placebo and GlucaGen? when administered as a rescue therapy for severe hypoglycemia in children with T1DM treated with insulin
This study will compare medications used to treat low blood sugars (hypoglycemia).
