Found 511 clinical trials
Phase 3 Accelerated BEP Trial: A randomised phase 3 trial of accelerated versus standard BEP chemotherapy for patients with intermediate and poor-risk metastatic germ cell tumours
The purpose of this study is to determine if accelerated BEP will be more effective but not significantly more toxic than standard BEP.
A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate Pembrolizumab Versus Placebo as Adjuvant Therapy Following Surgery and Radiation in Participants with High-risk Locally Advanced Cutaneous Squamous Cell Carcinoma(LA cSCC) (KEYNOTE-630).
The purpose of this study is to compare the recurrence-free survival (RFS), as assessed by the investigator and confirmed by biopsy, in individuals who receive pembrolizumab with individuals who receive placebo as adjuvant therapy.
ACCL1633, The Effectiveness of Lactobacillus plantarum in Preventing Acute Graft-versus-Host Disease (GvHD) in Children undergoing Alternative Hematopoietic Progenitor Cell Transplantation (HCT)
The purpose of this study is to find out if the probiotic Lactobacillus plantarum (LBP) will prevent the development of GI aGvHD in children, adolescents, and young adults undergoing alternative alloHCT.
Long-term Recovery in OUD
The goals of this project are: 1) Establish normative data on long-term recovery course of OUD across patients, community supports, and providers and 2) Quantify the impact of MAT on long-term recovery from OUD.
Tocotrienol Against the Progression of End Stage Liver Disease
The purpose of this study is to see if oral tocotrienol (TCT) will significantly reduce the rise in Model for End Stage Liver Disease (MELD) score over time in patients with Nonalcoholic Steatohepatits (NASH).
Effectiveness of two different forms of marine oil, derived from the New Zealand green lipped mussel (Perna canaliculus) and krill oil (Euphausia superba), on indirect markers of muscle damage and soreness during recovery from muscle damaging exercise in untrained men: a randomized controlled non-inferiority trial
The purpose of this study is to evaluate the effects of PCSO-524®, and a blend of PCSO-524® (75%) and krill oil (25%) (ESPO-572®), on indirect markers of muscle damage, inflammation and soreness during recovery from muscle damaging exercise.
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of Ataluren in Patients with Nonsense Mutation Duchenne Muscular Dystrophy and Open-Label Extension
This study is being done to see if Ataluren will slow the progression of DMD in boys with DMD who have specific mutations.
A Theoretically Informed mHealth Intervention to Improve Medication Adherence by Adults with Chronic Conditions: Technology Acceptance Model-Based Smartphone Medication Reminder App Training Session
As a potential way to support your medication taking and management, the aim of this study is to promote your smartphone medication reminder app use. To meet this aim, the purpose of this study is to provide you with a group session introducing a smartphone medication reminder app and to …
The OVAL Study: A Randomized, Controlled, Double-Arm,Double-Blind, Multi-Center Study of Ofranergene Obadenovec (VB-111) Combined with Paclitaxel vs. Paclitaxel Combined with Placebo for the Treatment of Recurrent Platinum-Resistant Ovarian Cancer
The purpose of this study is to compare the efficacy and safety of the experimental drug VB-111 in combination with the standard chemotherapy drug paclitaxel compared to using paclitaxel combined with placebo.
A Phase 2 Study of Sitravatinib in Combination with Nivolumab in Patients with Advanced or Metastatic Urothelial Carcinoma
The purpose of this study is to evaluate the clinical activity of sitravatinib in combination with nivolumab in patients with advanced or metastatic urothelial carcinoma.
