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Found 511 clinical trials

PHASE III RANDOMIZED TRIAL OF STANDARD SYSTEMIC THERAPY (SST) VERSUS STANDARD SYSTEMIC THERAPY PLUS DEFINITIVE TREATMENT (SURGERY OR RADIATION) OF THE PRIMARY TUMOR IN METASTATIC PROSTATE CANCER

The purpose of this study is to compare the effects, good and/or bad, of adding either prostate removal surgery or radiation therapy to standard systemic therapy (SST), which is used to treat prostate cancer.

18 years and older
All

Phase I/II Study of Ixazomib and Romidepsin in Relapsed/ Refractory Peripheral T-cell Lymphoma (PTCL)

The purpose of this study is to test the safety and efficacy of combining two drugs, ixazomib and romidepsin. It will also measure the percentage of patients whose tumor completely resolves after receiving ixazomib and romidepsin.

18 years and older
All

Cysview Blue Light Cystoscopy Registry

The purpose of this registry is to study the use of BLCC in clinical practice in the United States and to allow researchers access to this data to look at different clinical questions.

18 years and older
All

An open-label, Phase II, platform trial evaluating safety and efficacy of multiple BI 754091 anti-PD-1 based combination regimens in PD-(L)1 naïve and PD-(L)1 pretreated patient populations with advanced and/or metastatic solid tumours who have had at least one line of systemic therapy

This study is being done in subjects with advanced and/or metastatic solid tumors. The treatment-specific Module A portion of the study will test the combination of the investigational drugs BI 754091 and BI 754111.

18 years and older
All

Magnetic Resonance Imaging of the Brain and the Upper Gastrointestinal Tract in Healthy Volunteers and Patients with Gastroparesis

The purpose of this study is to examine the gastrointestinal (stomach and intestines) anatomy and function using magnetic resonance imaging (MRI).

18-65 years
All
Phase N/A

Phase I Study of Lonsurf in Combination with Gemcitabine and Nab-Paclitaxel in Patients with Advanced Pancreatic Ductal Adenocarcinoma (PDAC)

The purpose of this study is to see whether a chemotherapy drug called Lonsurf (TAS-102) could be given safely with other chemotherapy agents (gemcitabine and nab-paclitaxel), and to assess the good and bad effects this treatment might have. Gemcitabine and nab-paclitaxel are approved by the Food and Drug Administration (FDA) …

18 years and older
All

Russian Language Learning

The purpose of the study is examine the effect of learning a second language, in this case Russian, on brain structure and function.

18 years and older
All

Phase I trial of azacitidine plus nivolumab following reduced-intensity allogeneic PBSC transplantation for patients with AML and high-risk myelodysplasia

The purpose of this study is to find the maximum safe dose of nivolumab alone, and of nivolumab combined with azacitidine after reduced-intensity allogeneic peripheral blood stem cell (PBSC) transplantation. Another purpose is to see how the study drugs affect different aspects of transplant such as infection and disease response.

18 years and older
All

A Qualitative Inquiry on Amputation Decisions for Bone Cancer in the Lower Limb

The purpose of this study is to explore the lived experience and patient education (knowledge transfer) of patients and families when making a surgical decision for the treatment of osteosarcoma.

14 years and older
All

Black Educational Encouragement

You will be asked to participate in an online survey that assess your views and perceptions surrounding your experiences while in school as well as the ways you have attempted to overcome issues that have arose. 

18 years and older
All

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